Proarrhythmic Potential of Dronedarone: Emerging Evidence from Spontaneous Adverse Event Reporting
نویسندگان
چکیده
منابع مشابه
Simulating adverse event spontaneous reporting systems as preferential attachment networks: application to the Vaccine Adverse Event Reporting System.
BACKGROUND Spontaneous Reporting Systems [SRS] are critical tools in the post-licensure evaluation of medical product safety. Regulatory authorities use a variety of data mining techniques to detect potential safety signals in SRS databases. Assessing the performance of such signal detection procedures requires simulated SRS databases, but simulation strategies proposed to date each have limita...
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INTRODUCTION Spontaneous reporting of adverse drug reactions (ADRs) is used for continuous risk-benefit evaluation of marketed pharmaceutical products and for signal detection. The Adverse Drug Event Manager (ADEM) is a service offered to clinicians employed at hospitals in the Capital Region of Denmark. The ADEM assists healthcare professionals in reporting suspected ADRs to the Danish Health ...
متن کاملAntipsychotics and Torsadogenic Risk: Signals Emerging from the US FDA Adverse Event Reporting System Database
BACKGROUND Drug-induced torsades de pointes (TdP) and related clinical entities represent a current regulatory and clinical burden. OBJECTIVE As part of the FP7 ARITMO (Arrhythmogenic Potential of Drugs) project, we explored the publicly available US FDA Adverse Event Reporting System (FAERS) database to detect signals of torsadogenicity for antipsychotics (APs). METHODS Four groups of even...
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در این تحقیق به مطالعه وجود انتخاب نامساعد(کژ گزینی) در بازار بیمه درمان تکمیلی ایران پرداخته شده است. داده های مورد نیاز توسط پرسشنامه و به روش نمونه گیری خوشه ای جمع آوری شده است. پرسشنامه ها در میان افراد شاغل ساکن شهر تهران توریع شد. در این تحقیق با استفاده از تخمین دو مدل لجستیک و به دست آوردن ضریب همبستگی میان تقاضای بیمه درمان تکمیلی و رخداد خسارت به بررسی موضوع مورد نظر پرداخته شده است....
15 صفحه اولSpontaneous reporting of fatal adverse drug reactions.
179 Many countries run schemes which encourage physicians and other health care professionals to report suspected drug reactions (ADRs). The aims of these spontaneous reporting schemes (SRSs) are to identify previously unsuspected reactions, to elucidate the relevant risk factors, and to evaluate the comparative toxicity of drugs within the same therapeutic class [1,2]. By their nature these sc...
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ژورنال
عنوان ژورنال: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
سال: 2012
ISSN: 0277-0008
DOI: 10.1002/j.1875-9114.2012.01118.x